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have raised concerns about increasing prevalence of depression among adolescents.Yet, there is little direct information from the United States on national trends in prevalence of depression in adolescents and young adults.

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We limited the analyses of these questions to participants with 12-month MDE.

Substance use disorder ratings were based on individual diagnostic criteria from the on past 12-month abuse and dependence of alcohol, marijuana, and other drugs (including cocaine, hallucinogens, heroin, inhalants, non–medically used prescription pain relievers, sedatives, tranquilizers, or stimulants).

It provides nationally representative data on MDE and its treatment among the civilian noninstitutionalized population aged 12 or older.

Persons without a household address (eg, homeless persons not living in shelters), active-duty military, and institutional residents are excluded.

Substance use disorders were categorized into alcohol use disorder only, cannabis use disorder (without alcohol use disorder), other drug use disorder (without alcohol use disorder), and any drug use disorder with alcohol use disorder.

Information also was collected on participant age, sex, race/ethnicity, annual family income, student status, parents in the household (for adolescents), employment status (for those aged 14 ) and marital status (adults). First, trends in the prevalence of 12-month MDE across the 10 years of NSDUH were assessed by using adjusted binary logistic regression models.

Trends in service use also are evaluated by type of provider, type of setting, use of psychiatric medications, continuation of treatment, and perceived helpfulness of treatments.

The NSDUH is a cross-sectional annual survey of the US population in all 50 states and the District of Columbia sponsored by Substance Abuse and Mental Health Services Administration.

The findings call for renewed efforts to expand service capacity to best meet the mental health care needs of this age group.

There is evidence of increased prevalence of depressive symptoms in adolescents in industrialized countries in past 3 decades.

Recent suicide trends in the United States suggest that depression in adolescents and young adults may have continued to increase.

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